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"Inverted Culture Microscope for Cell Observation in Labs"

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"Educational Lab Inverted Microscope with Long Working Distance"

Buy Inverted Culture Biological Microscope – ESAW Precision for Research & Lab Use

Model No : NIB-600

Regular price Rs. 749,999.00
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3-5 Working Days

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3 Days Replacement as standard, Free of Cost

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Description
    Technical Specifications Overview
    Inverted Culture Biological Microscope
    Eyepieces Wide field paired 10x (anti-fungus)
    Objectives Long Working Distance Achromatic (10x, 25x, 40x)
    Viewing Head Monocular Inverted Body
    Stage Mechanical Stage
    Condenser Working Distance 72 mm
    Illumination LED
    Catalog No. ESAW-ICBM
    Quantity per Case 1 Unit

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    Significance

    The **Inverted Culture Biological Microscope** holds immense significance in modern biological and medical research, specifically because its **objective lenses are positioned beneath the specimen**. Unlike conventional upright microscopes, this inverted design allows scientists to observe cells and living organisms growing at the bottom of large culture flasks, petri dishes, or microplates. This capability is absolutely non-negotiable for **Tissue Culture (TC) and In Vitro Fertilization (IVF) laboratories**.

    In major research hubs like **Mumbai, Chennai, and Hyderabad**, where biotechnology and advanced pathology are flourishing, the ability to monitor the health, growth, and morphology of delicate cell lines—without disturbing the sterile culture environment—is paramount. The inverted configuration is also designed to accommodate accessory features like **Phase Contrast** and specialized fluorescence units, essential for detailed analysis of cellular components and processes, thereby securing its place as an indispensable research tool across India and global academic centers.

    Uses

    The primary uses of the Inverted Culture Microscope are centered around the observation of living cells in their natural growth environment. Key applications include:

    • **Routine Cell Culture Monitoring:** Daily inspection of cell confluence, detection of microbial or fungal contamination, and checking for cellular health in research labs across **Pune** and **Bengaluru**.
    • **IVF and Reproductive Biology:** Used for handling and observing oocytes, sperm, and early stage embryos in fertilization and micromanipulation procedures. Its long working distance is crucial here.
    • **Immunofluorescence and Live Imaging:** The stable platform and ease of integrating specialized light sources make it ideal for time-lapse studies of dynamic processes in living cells.
    • **Micro-Injection Techniques:** Providing the necessary optical clarity and working space to perform micro-injection of foreign substances (like DNA or drugs) into individual cells.

    Its application in educational institutions, especially those in **North Indian states** emphasizing life sciences, provides students with firsthand experience in professional cell handling protocols.

    Applications

    The wide-ranging applications of this specialized microscope span clinical diagnostics, drug development, and academic research:

    Specific applications include:

    • **Virology:** Observing the cytopathic effects (CPE) of viruses on host cell lines, a core procedure in many public health labs.
    • **Toxicology Screening:** Assessing the impact of potential new drugs or toxins on cell viability and morphology, crucial for pharmaceutical R&D in states like **Gujarat** and **Himachal Pradesh**.
    • **Electrophysiology:** Used as a stable observation platform during patch-clamping experiments on live neurons or cardiac cells.
    • **Stem Cell Research:** Critical for maintaining and characterizing undifferentiated stem cell colonies grown in culture, ensuring quality control in advanced therapy labs nationwide.

    The flexibility in handling large vessels (like T-75 flasks) makes it an essential workhorse, delivering reliability and superior image quality necessary for Google ranking optimization related to high-end laboratory equipment.

    Key Questions About Inverted Microscopy

    1. Why must the objectives be under the specimen? Cells in culture grow attached to the bottom surface of a vessel (e.g., petri dish). The inverted design places the objectives closest to the cells, looking up through the thin glass/plastic bottom, which is essential for observing them while they remain in their culture medium.
    2. Can it be used with standard glass slides? Yes, it can. While optimized for large cell culture vessels, adapters and special holders allow standard slides to be placed on the stage, provided the stage platform is adjusted for the required working distance.
    3. What special features are necessary for an Inverted Culture Microscope? It requires a **Long Working Distance (LWD)** objective set (to accommodate the thickness of the culture vessel and medium) and a large, fixed stage for accommodating large flasks and multi-well plates. Phase Contrast is almost always included.
    4. Is Phase Contrast commonly used with this microscope? Absolutely. Live cells in culture are typically transparent and unstained. Phase Contrast is the primary technique used with inverted microscopes to create the necessary contrast to see these transparent cells and their internal components clearly and non-destructively.
    5. How does this model aid in IVF procedures? In IVF (In Vitro Fertilization) labs, the inverted microscope provides the stable, high-magnification view needed to perform highly delicate procedures like ICSI (Intracytoplasmic Sperm Injection) and embryo grading while the cells are in their culture dishes.

    Global Export and Indian State Distribution

    • INDIA (All States including Maharashtra, Karnataka, Delhi, Tamil Nadu)
    • United States
    • Germany
    • United Kingdom
    • France
    • Italy
    • Spain
    • Brazil
    • Mexico
    • Canada
    • Australia
    • New Zealand
    • China
    • Japan
    • South Korea
    • Singapore
    • Malaysia
    • UAE
    • Saudi Arabia
    • South Africa

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